Parameter (Units) (Ref. range/cutoff)

Treatment

Placebo

Ginkgo biloba Extract

P value

Compliance rate (%)

93 ± 0.1

94.0 ± 0.1

0.286

Age (years)

45.7 ± 9.9

Body Mass Index (kg/m²)

29.8 ± 6.2

29.9 ± 6.2

0.350

Systolic blood pressure (mm Hg) (<120)

128 ± 15

123 ± 12

0.046^*

Diastolic blood pressure (mm Hg) (<80)

76 ± 11

74 ± 9

0.083

Hemoglobin A_1c (%) (4.2 - 5.8)

5.3 ± 0.4

5.5 ± 0.4

0.190

Fasting Insulin (mU/L) (2 - 25)

8 ± 5

10 ± 7

0.025^*

Fasting C-peptide (mg/L) (<4)

2.0 ± 1.6

2.5 ± 1.3

0.049^*

Total cholesterol (mg/dl) (<5.18)

4.84 ± 1.01

5.02 ± 0.98

0.121

Triglycerides (nmol/L) (<2.03)

1.27 ± 0.82

1.37 ± 0.76

0.232

HDL-Cholesterol (nmol/L) (>0.91)

1.30 ± 0.26

1.32 ± 0.28

0.298

LDL-Cholesterol (mg/dl) (<3.37)

3.00 ± 0.75

3.08 ± 0.80

0.288

Fibrinogen (g/L) (1.98 - 5.24)

2.89 ± 0.71

2.94 ± 0.63

0.318

PT (s) (10.8 - 13.4)

11.9 ± 1.3

11.9 ± 1.2

0.419

PTT(s) (20.0 - 31.6)

28.5 ± 2.4

28.9 ± 1.1

0.380

Fasting glucose (nmol/L) (3.89 - 5.83)

5.05 ± 0.50

5.22 ± 0.50

0.067

Glucose AUC_0-2 (nmol/L/h)

14.93 ± 2.61

15.15 ± 2.55

0.277

Fasting cortisol (nmol/L) (138 - 635)

326 ± 149

268 ± 121

0.019^*

Cortisol AUC_0-2 (nmol/L/h)

668 ± 265

530 ± 213

0.001^*